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Zhou Research Group
>>Research
Publications
*2024*
64.Li, M.; Zeng, W.; Abdukader, A.;* Wu, S.; Zhou, L.*
Base-Mediated Regioselective [3 + 3] Annulation of Alkylidene Malononitriles with Trifluoromethyl Alkenes via Dual C-F bond Cleavage.
Org. Lett.
,
2024
,
10.1021/acs.orglett.4c02788.
63.Li, H.; Abdukader, A.;* Zhou, L.*
Radical Denitrogenative Ring Opening of N-Benzyl-benzotriazoles for the Synthesis of 6-Substituted Phenanthridines Under Visible Light Conditions.
Chin. J. Org. Chem.
,
doi: 10.6023/cjoc202403008.
62.Li, S.; Ling, J.; Zhou, L.*
Visible-Light-Promoted Radical gem-Selenosulfonylation or Iodosulfonylation of 2,2,2-Trifluorodiazoethane under Photosensitizer-free Conditions.
Org. Lett.
,
2024
,
26, 5220-5225.
61.Zeng, W.; Li, M.; Wu, S.; Abdukade, A.;* Zhou, L.*
Regioselective Difluoroallylation of Alkylidenemalonates with Trifluoromethyl Alkenes: Synthesis of gem-Difluoro-1,5-Dienes and Their [2 + 2] Photocycloaddition.
Org. Chem. Front.
,
2024
,
11, 3421-3426.
60.Li, S.; Zhou, L*
Photocatalytic (3+3) Annnulation of Vinyldiazo Compounds and Aminocyclopropanes.
Org. Lett.
,
2024
,
26, 3294-3298.
59.Tan, H.; Li, H.; Wu, S.; Abdukade, A.;* Zhou L.*
Synthesis of gem-Difluorocyclobutane-Fused Indolines via Ruthenium-Catalyzed Defluorinative Annulation of Trifluoromethyl Carbenoids with 2-Alkenylanilines.
Adv. Synth. Catal.
,
2024
,
366, 1059-1063.
(Very Important Publication)
58.Ling, J.; Zhou, L.*
Picking Two out of Three: Defluorinative Annulation of Trifluoromethyl Alkenes for the Synthesis of Monofluorinated Carbo and Heterocycles.
Chem. Rec.
,
2024
,
e202300332
57. Lin, D.; Lin. B.; Wang, X.; Xu, C.; Mo, L.; Luo, Y.; Tian, H.; Zhou, L.*; Chen, Z.*
Mycobacterium marinum mediates regulation of prostaglandin E2 expression on host immune response through cyclooxygenase pathway.
Mol. Biol. Rep.
,
2024
,
51, 84.
*2023*
56.Li, S.; Zhou, L.*
gem-Difluoro-Masked o-Quinone Methides Generated by Photocatalytic Radical (3+3) Annulation and Their (4+1) Cycloaddition with Sulfur Ylides.
Org. Lett.
,
2023
,
25, 8700-8705.
55.Zeng W.; Li, H.; Wang, D.*; Zhou, L*
Regioselective Synthesis of 3-Trifluoromethylpyrroles by [3+2] Cycloaddition of N-Acyl -Amino Acids and 2-Bromo-3,3,3-trifluoropropene.
J. Org. Chem.
,
2023
,
88, 14088-14095
(highlighted by Synfacts, 2024, 20, 10.)
54.Li, W.; Li, S.; Empel, C.; Koenigs, R. M.* Zhou L;*
Photoredox-Enabled Self-(3+2) Cyclization of Vinyldiazo Reagents: Synthesis of Cyclopentenyl α-Diazo Compounds
Angew. Chem. Int. Ed.
,
2023
,
e202309947.
53. Tian, J.; Zhou, L.*
Photoredox Radical/Polar Crossover Enables C-H gem-Difunctionalization of 1,3-Benzodioxoles for the Synthesis of Monofluorocyclohexenes
Chem. Sci.
,
2023
,
14, 6045–6051
52.He X.; Lin, J.; Fang, Z.; Zhou, L.*
Synthesis of 2-Fluorobenzofuran by Photocatalytic Defluorinative Coupling and 5-endo-trig Cyclization
J. Org. Chem.
,
2023
,
88, 7586−7591
51.Li, H.; Mei. M.; Wang, D.; Zhou, L*
Synthesis of mono-fluorinated heterocycles with a ring-junction nitrogen atom via Rh(III)-catalyzed CF3-carbenoid C–H functionalization and defluorinative annulation.
Org. Chem. Front.
,
2023
,
10, 1544–1550
*2022*
50. Li. S.; Zhou, L.*
Visible Light-Promoted Radical Reactions of Diazo Compounds.
Chin. J. Org. Chem.
,
2022
,
42, 3944-3958
49.Li, H.; Mei, M.; Zhou, L.*
Rh(III)-Catalyzed Defluorinative [4 + 2] Annulation of N‑Sulfonylarylamides with Ethyl 2-Diazo-3,3,3-trifluoropropanoate: Synthesis of 1,3,4-Functionalized Isoquinolines.
Org. Lett.
,
2022
,
24, 8969-8974.
48.Zeng, W.; Li, L.; Wang, C.; Wang, D.; Zhou, L.*
Synthesis of 3-Amino-1-(difluoromethylidene)tetralins via Relay Photocatalytic Cascade Reactions of Arylalanines and 2-Bromo-3,3,3-trifluoropropene.
Adv. Synth. Catal.
,
2022
,
364, 3310-3315.
47.Li, W.; Chen, X.; Zhou, L.*
Photocatalytic Defluorinative Three-Component Reaction of α-Trifluoromethyl Alkenes, Alkenes, and Sodium Sulfinates: Synthesis of Monofluorocyclopentenes.
Org. Lett.
,
2022
,
24, 5946−5950.
46.Li, W.; Zhou, L.*
Synthesis of Tetrasubstituted Allenes via Visible-Light-Promoted Radical 1,3-Difunctionalization of Alkynyl Diazo Compounds.
Org. Lett.
,
2022
,
24, 3976–3981.
45.Zeng, W.; Li, W.; Chen, H. Zhou, L.*
Relay Photocatalytic Reaction of N-Aryl Amino Acids and 2-Bromo-3,3,3-trifluoropropene: Synthesis of 4-(Difluoromethylidene)- tetrahydroquinolines.
Org. Lett.
,
2022
,
24, 3265−3269.
44.Sun, Z.; Zhou, L.*
Synthesis of 5‑Fluoro-dihydroindolizines from Pyrrole-2-acetic Acids and Trifluoromethyl Alkenes via Dual C−F Bond Cleavage in a CF3 Group.
J. Org. Chem.
,
2022
,
87, 4801−4812.
43.Tian, J.; Sun, Z.; Li, W.; Wang, D.*; Zhou, L.*
Visible-light-promoted defluorinative ring-opening gem-difluoroallylation of cycloalkanols using 1-trifluoromethyl alkenes.
New J. Chem.
,
2022
,
46, 8545−8550.
*2021*
42. Zhou, L.*
Recent Advances in C-F Bond Cleavage Enabled by Visible Light Photoredox Catalysis.
Molecules
,
2021
,
26
7051.
41. Li, W.; Zhou, L.*
Visible-light-driven radical 1,3-addition of selenosulfonates to vinyldiazo compounds.
Green. Chem.
,
2021
,
DOI: 10.1039/d1gc02036f
40. 周磊
绿色化学的若干衡量指标.
大学化学
,
2021
,
36 (6):
2007030.
39. Li, W.; Xu, H.; Zhou, L.*
Acid-catalyzed oxidative cross-coupling of acridans with silyl diazoenolates and a Rh-catalyzed rearrangement: two-step synthesis of γ-(9-acridanylidene)-β-keto esters.
Org. Biomol. Chem.
,
2021
,
19,
5649–5657.
38. Li, W.; Zhou, L.*
Vinyldiazo Compounds as 3‑Carbon Radical Acceptors: Synthesis of 4‑Fluoroacridines via Visible-Light-Promoted Cascade Radical Cyclization
Org. Lett.
,
2021
,
23,
4279−4283.
37. Li, W.; Zhou, X.; Xiao, T.; Ke, Z.*; Zhou, L.*
External Photocatalyst-free, Visible Light-Promoted 1,3-Addition of Perfluoroalkyl Iodides to Vinyldiazoacetates
CCS Chem.
,
2021
,
3,
794-805.
*2020*
36. Anand, D.; Sun. Z.; Zhou, L.*
Visible-Light-Mediated β-C–H gem-Difluoroallylation of Aldehydes and Cyclic Ketones through C–F Bond Cleavage of 1-Trifluoromethyl Alkenes.
Org. Lett.
,
2020
,
22
DOI: 10.1021/acs.orglett.0c00568.
35. Xiao, T.*; Huang, H.; Anand, D.; Zhou, L.*
Iminyl-Radical-Triggered C–C Bond Cleavage of Cycloketone Oxime Derivatives: Generation of Distal Cyano-Substituted Alkyl Radicals and Their Functionalization.
Synthesis
,
2020
,
DOI: 10.1055/s-0039-1690844
*2019*
34. He, Y.; Anand, D.; Sun. Z.; Zhou, L.*
Visible-Light-Promoted Redox Neutral γ,γ-Difluoroallylation of Cycloketone Oxime Ethers with Trifluoromethyl Alkenes via C–C and C–F Bond Cleavage.
Org. Lett.
,
2019
,
21
,3769−3773.
33. Mei, M.; Anand, D.; Zhou, L.*
Divergent Conversion of N-Acyl-isoxazol-5(2H)-ones to Oxazoles and 1,3-Oxazin-6-ones Using Photoredox Catalysis,
Org. Lett.
,
2019
,
21
,3548−3553.
32. Chen. H.; Anand, D.; Zhou, L.*
Photoredox Defluorinative Alkylation of 1-Trifluoromethyl Alkenes and 1,3-Butadienes with 1,4-Dihydropyridines as Alkylation Reagents
Asian J. Org. Chem.
,
2019
,
8
, 661–664.
Invited contribution to the special issue on Organofluorine Chemistry.
31. Anand, D.; He, Y.; Li, L.; Zhou, L.*
A photocatalytic sp3 C–S, C-Se and C-B bonds formation through C–C bond cleavage of cycloketone oxime esters.
Org. Biomol. Chem.
,
2019
,
DOI: 10.1039/C8OB02987C.
*2018*
30. Chen. H.; He, Y.; Zhou, L.*
A photocatalytic decarboxylative/defluorinative [4 + 3] annulation of o-hydroxyphenylacetic acids and trifluoromethyl alkenes: synthesis of fluorinated dihydrobenzoxepines.
Org. Chem. Front.
,
2018
,
5
, 3240-3244.
29. Xiao, T.; Mei, M.; He, Y.;* Zhou, L.*
Blue light-promoted cross-coupling of aryldiazoacetates and diazocarbonyl compounds.
Chem. Commun.
,
2018
,
54
,8865-8868.DOI: 10.1039/c8cc04609c.
28.He, Y.; Chen, H.; Li, L.; Huang, J.; Xiao, T.; Anand, D.; Zhou, L.*
Visible Light-promoted Radical Benzannulation of Diazoketones with Alkynes Leading to Polysubsituted Naphthols. Special issue for Professor Chen-Ho Tung on the occasion of his 80
th
birthday.
J. Photochem. Photobiol. A,
2018
,
355
, 220-225.
*2017*
27.Li, L.; Chen, H.; Mei, M.; Zhou, L.*
Visible-light promoted γ-cyanoalkyl radical generation: three-component cyanopropylation/etherification of unactivated alkenes.
Chem. Commun.,
2017
,
53
, 11544-11547.
26.Chen, H.; Xiao, T.; Li, L.; Anand, D.; He, Y.; Zhou, L.*
Synthesis of Fluorinated Benzo[a]quinolizidines via Visible Light-induced Tandem Substitution of Two Fluorine Atoms in a CF
3
Group.
Adv. Synth. Catal.,
2017
,
359
, 3642-3647.
25.Huang, J.; Li, L.; Chen, H.; Xiao, T.; He, Y.; Zhou, L.*
Synthesis of 3-Aryl-2-pyrones by Palladium-catalyzed Cross-coupling of Aryl Iodides with Cyclic Vinyldiazo Ester.
J. Org. Chem.,
2017
,
82
, 9204-9209.
24.Huang, J.; Chen. H.; Li, L.; Xiao, T.; He, Y.; Zhou, L.*
Silver-Catalyzed Geminal Aminofluorination of Diazoketones with Anilines and N-Fluorobenzenesulphonimide.
Org. Chem. Front.,
2017
,
4
, 529-533.
23. Li, L.; ║ Xiao, T.; ║ Chen. H.; Zhou, L.*
Visible Light-mediated Twofold Unsymmetrical Sp
3
C-H Functionalization and Double C-F Substitution.
Chem. Eur. J.,
2017
,
23
, 2249–2254.
*2016*
22.Huang, J.; Li, L.; Xiao, T.; Mao, Z.-W.; Zhou, L.;*
Redox-neutral C1 Functionalization of Unprotected Tetrahydroisoquinolines with Diazo Carbonyl Compounds.
Asian. J. Org. Chem.,
2016
,
5
, 1204-1207.
21.Xiao. T.;║ Li, L.; ║ Zhou, L.*
Synthesis of Functionalized gem-Difluoroalkenes via A Photocatalytic Decarboxylative/Defluorinative Reaction.
J. Org. Chem.,
2016
,
81
, 7908-7916.
20.Xiao, T.; Li, L.; Xie, Y.; Mao, Z.-W.; Zhou, L.*
Synthesis of Gem-Difluorinated Fused Quinolines via Visible Light-Mediated Cascade Radical Cyclization.
Org. Lett.,
2016
,
18
, 1004-1007.
19.Xie, Y.; Zhang, P.; Zhou, L.*
Regiospecific Synthesis of Benzoxepines through Pd-Catalyzed Carbene Migratory Insertion and C-C Bond Cleavage.
J. Org. Chem.
,
2016
,
81
, 2128-2134.
18.Liu, Y.; Dong, X.; Deng, G.;* Zhou, L.*;
Synthesis of aziridines by visible-light induced decarboxylative cyclization of N-aryl glycines and diazo compounds.
Sci. China. Chem.
,
2016
,
59
, 199-202. Invited contribution to the special issue on Organic Photochemistry.
17.Zhou, L.;* Hossain, M. L.; Xiao, T.;
Synthesis of N-Containing Heterocyclic Compounds Using Visible-Light Photoredox Catalysis.
Chem. Rec.,
2016
,
16
, 319-334. Invited Personal Account.
*2015*
16.Xiao, T.; Peng, P.; Xie, Y.; Wang, Z.-Y.; Zhou, L.*;
Ag(I)-Catalyzed Three-component Reaction of 2-Alkynylbenzaldehydes, Amines and Diazo Compounds.
Org. Lett.,
2015
,
17
, 4332-4335.
15.Wang, Q.; Huang, J.; Zhou, L.*;
Synthesis of Quinolines by Visible-Light Induced Radical Reaction of Vinyl Azides and α-Carbonyl Benzyl Bromides.
Adv. Synth & Catal.,
2015
,
357
, 2479-2484.
14.Dong, X.; Hu, Y.; Xiao, T.; Zhou, L.*;
Synthesis of 2-trifluoromethyl indoles via visible light induced intramolecular radical cyclization.
RSC Adv.
,
2015
,
5
, 39625-39629.
13.Ye, F.;Qu, S.Zhou, L.;Peng, C.; Wang, C.; Cheng, J.; Hossain, M. L.; Liu, Y.; Zhang, Y.; Wang, Z.-X.;* Wang, J.*;
Palladium-catalyzed C-H functionalization of acyldiazomethane and tandem cross-coupling reactions.
(co-first authors)
J. Am. Chem. Soc.,
2015
,
137
, 4435-4444.
*2014*
12.Xiao. T.; Li, L.; Lin, G.; Mao. Z.-W.; Zhou, L.*;
Metal-Free visible-light induced cross dehydrogenative coupling of tertiary amines with diazo compounds.
Org. Lett.,
2014
,
16
, 4232-4235.
11.Xiao, T.; Zhang, P.; Xie, Y.; Wang, J.; Zhou, L.*;
CuI-catalyzed cross-coupling of terminal alkynes with dialkoxycarbenes: a general method for the synthesis of unsymmetrical propargylic acetals.
Org. Biomol. Chem.
2014
,
12
, 6215–6222.
10.Zhang, P.; Xiao, T.; Xiong, S.; Dong, X.; Zhou, L.*;
Synthesis of 3-acylindoles by visible-light induced intramolecular oxidative cyclization of
o
-alkynylated N,N-dialkylamines.
Org. Lett.
2014
,
16
, 3264-3267.
9.Xiao. T.; Li, L.; Lin, G.; Wang, Q.; Zhang. P.; Mao. Z.-W.*; Zhou, L.*;
Synthesis of 6-substituted phenanthridines by metal-free, visible-light induced aerobic oxidative cyclization of 2-isocyanobiphenyls with hydrazines.
Green. Chem.
2014
,
16
, 2418 – 2421.
*2013*
8.Zhou, L.; Liu, Z.; Liu, Y.; Zhang, Y.*; Wang, J.*;
N-Tosylhydrazine-mediated deoxygenative hydrogenation of aldehydes and ketones catalyzed by Pd/C.
Tetrahedron
2013
,
69
, 6083-6087.
7.Dong, X.; Xu. Y.; Liu, J.; Hu, Y.; Xiao, T.; Zhou. L.*;
Visible-light-induced Radical Cyclization of Trifluoroacetimidoyl Chlorides with Alkynes: Catalytic Synthesis of 2-Trifluoromethyl Quinolines.
Chem. Eur. J.
2013
,
19
, 16928-16933.
6.Wang. Q.; Dong, X.; Xiao, T.; Zhou. L.*;
PhI(OAc)
2
-mediated synthesis of 6-(trifluoromethyl) phenanthridines by oxidative cyclization of 2-isocyanobiphenyls with CF
3
SiMe
3
under metal-free conditions.
Org. Lett.
2013
,
15
, 4846-4849.
5.Xiao. T.; Xiong, S.; Xie, Y.; Dong, X.; Zhou. L.*;
Copper-catalyzed synthesis of benzazoles via aerobic oxidative condensation of o-amino/ mercaptan / hydroxyanilines with benzylamines.
RSC Adv.
,
2013
,
3
, 15592-15595.
4.Xiao. T.; Dong, X.; Zhou, L.*;
Benzofuran and indole synthesis via Cu(I)-catalyzed coupling of N-tosylhydrazone and
o
-hydroxy or
o
-amino phenylacetylene.
Org. Biomol. Chem.
,
2013
,
11
, 1490-1497.
*2012*
3.Tang. Y.; Xiao, T.; Zhou, L.*;
Cobalt-catalyzed alkyne–dihalomethane–amine coupling: an efficient route for propargylamines.
Tetrahedron Lett.
,
2012
,
53
, 6199-6201.
2.Xiao, T.; Dong, X.; Tang, Y.; Zhou, L.*;
Phenanthrene synthesis by eosin Y-catalyzed, visible- light-induced [4 + 2] benzannulation of biaryl diazonium salts with alkynes.
Adv. Synth & Catal.
2012
,
354
, 3195-3199.
1.Zhou, L.; Ye, F.; Zhang, Y.; Wang, J.*;
Cyclopropylcarbinylpalladium species from carbene migratory insertion: new routes to 1, 3-butadienes.
Org. Lett.
2012
,
14
, 922-925.
*Selected Publications Before 2012*
1.Zhou, L.; Ye, F.; Ma, J.; Zhang, Y.; Wang, J.*;
Pd-Catalyzed oxidative cross-coupling of N-tosylhydrazones or diazoesters with terminal alkynes: a new route to conjugated enynes
Angew. Chem. Int. Ed.
2011
,
50
, 3510-3514.
2.Zhou, L.; Shi. Y.; Liu, Y.; Ye, F.; Zhang, Y.; Wang, J.*;
CuBr-catalyzed coupling of N-tosylhydrazone and terminal alkyne: synthesis of benzofuran and indole
Org. Lett.
2011
,
13
, 968-971.
3.Zhou, L.; Liu, Y.; Zhang, Y.; Wang, J.*;
Pd-catalyzed coupling of
β
-hydroxy
α
-diazocarbonyl compounds with aryl iodides: a migratory insertion/
β
-hydroxy elimination sequence.
Chem. Commun.
2011
,
47
, 3622-3624.
4.Zhou, L.; Ma, J.; Zhang, Y.; Wang, J.*;
Copper-Catalyzed Cascade Coupling/Cyclization of Terminal Alkynes with Diazoacetates: A Straightforward Route for Trisubstituted Furans
Tetrahedron Lett.
2011
,
52
, 5484-5487.
5.Zhou, L.; Liu, Y.; Zhang, Y.; Wang, J.*;
Sequential Au(I)-Catalyzed Reaction of Water with
o
-Acetylenyl-Substituted Phenyldiazoacetates
Beilstein J. Org. Chem.
2011
,
7
, 631-637.
(Invited Contribution for "Gold Catalysis for Organic Synthesis as a Thematic Series")
6.Zhou, L.; Ye, F.; Zhang, Y.; Wang, J.*;
Pd-catalyzed three-component coupling of N-tosylhydrazone, terminal alkyne, and aryl halide
J. Am. Chem. Soc.
2010
,
132
,13590-13591
(The top 5 most read paper)
7.Zhou, L.; Shuai, Q.; Jiang, H-F.*; Li, C-J.*;
Diastereoselective synthesis of
γ
,
δ
-alkynyl-
β
-amino acid derivatives by a Cu-catalyzed amine-alkyne-alkyne addition reaction
Chem. Eur. J.
2009
,
15
,11668-11674
8.Zhou, L.; Jiang, H-F.*; Li, C-J.*;
Efficient Synthesis of
γ
,
δ
-Alkynyl-
β
-amino Acid Derivatives by a New Copper-Catalyzed Amine-Alkyne-Alkyne Addition Reaction
Adv. Synth & Catal.
2008
,
350
,2226-2230.
9.Zhou, L.; Chen, L.; Skouta, R.; Jiang, H-F.*; Li, C-J.*;
Palladium-catalyzed 1,4- Addition of terminal alkynes to unsaturated carbonyl compounds promoted by electron-rich ligands
Org. Biomol. Chem.
2008
,
6
,2969-2977.
10.Zhou, L.; Jiang, H-F.*; Li, C-J.*;
Synthesis of propargylamines by a copper-catalyzed tandem anti-Markovnikov hydroamination and alkyne addtion
Synlett
2009
, 937-940.
11.Zhou, L.; Jiang, H-F.*;
Synthesis of phthalides via Pd/CNTs-catalyzed reaction of terminal alkynes and
o
-iodobenzoic acid under copperand ligand-free conditions.
Tetrahedron Lett.
2007
,
48
,8449-8452.
12.Huang, J-M.; Zhou, L.; Jiang, H-F.*;
PdCl
2
/CuCl
2
-catalyzed allylation of alkynes with allyl alcohol in aqueous media: highly regio- and steroslective synthesis of 1,4-dienes.
Angew. Chem. Int. Ed.
2006
,
45
,1945-1949.
◇Copyright: Zhou Research Group ◇